p27(Phospho Ser10) Polyclonal Antibody, 50ul sgRNA Oligos Mutations in this gene result

Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease

the basic N-terminus is highly homologous to the N-terminus of a related gene

Catalytic activity of this enzyme promotes its nuclear localization

colon and leukocytes

Mutations at this locus have been associated with Rett syndrome

p27(Phospho Ser10) Polyclonal Antibody, 50ul sgRNA Oligos Mutations in this gene resultThis gene encodes a cyclin dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A p21. The encoded protein binds to and prevents the activation of cyclin E CDK2 or cyclin D CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from